Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cells

A dried powder from basidiomycetous fungi, Ganoderma lucidum, has been used in East Asia in therapies for several different diseases, including cancer. However, the molecular mechanisms involved in the biological actions of Ganoderma are not well understood. We have recently demonstrated that phosphatidylinositol 3-kinase (PI 3-kinase) and nuclear factor-?B (NF-?B) regulate motility of highly invasive […]

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