Effects of dietary flavonoids, luteolin and quercetin on the reversal of epithelial-mesenchymal transition in A431 epidermal cancer cells

Highly invasive A431-III cells, which are derived from parental A431-P cells, were originally isolated via three successive passages through a Boyden chamber using a Matrigel-coated membrane support. The greater invasion potential exhibited by A431-III cells was due to their increased ability to spread/migrate, which was associated with enhanced MMP activity. The tumor progression events evoked […]

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