Cancer as a metabolic disease: implications for novel therapeutics

Seyfried TN, Flores RE, Poff AM & D’Agostino DP. Carcinogenesis (2013) doi: 10.1093/carcin/bgt480 Full text available at: http://carcin.oxfordjournals.org/content/early/2014/01/18/carcin.bgt480.full Emerging evidence indicates that cancer is primarily a metabolic disease involving disturbances in energy production through respiration and fermentation. The genomic instability observed in tumor cells and all other recognized hallmarks of cancer are considered downstream epiphenomena of […]

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