Transcription factor ATF3 links host adaptive response to breast cancer metastasis

Wolford CC, McConoughey SJ, Jalgaonkar SP, et al. J Clin Invest. 2013;123(7):2893–2906. doi:10.1172/JCI64410. Cancers are not simply autonomous masses of cells; they secrete soluble factors to elicit systemic responses from the host, and the host responses, in turn, affect cancer cells (1–6). A key target tissue for cancer cells to modulate the host is the […]

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