Smaller retailers are suffering from a lack of human capital

25th Friday, 2013  |   Uncategorized  |  no comments

In addition, she notes, while the nation small mom and pop stores remain entrenched, in the future they will consolidate as shop owners die out and their children decline to take over the family business. Smaller retailers are suffering from a lack of human capital. The children have gotten a higher education and have gone off to work in corporations,combined with the fact that they have fewer children than the last generation.

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Wei Tang, who works on Love team as Specialized dedicated liaison to Alibaba Group sites, says that in the first seven months of 2015, he got more than $5 million in fake inventory delisted just from Alibaba websites. Specialized knocks down about $15 million a year total in counterfeit sales, across more than 80 platforms. In a written response to our request for comment Hermes Outlet Australia, Candice Huang, a spokesperson for the Alibaba Group, said that it has more than 2,000 staff devoted to fighting counterfeit on its sites, a problem that founder Jack Ma has called cancer.

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This unprecedented demand for high end branded items has actually resulted in a simultaneous increase in the fake luxury segment in astounding numbers. The Indian fake luxury market is set to double to Rs 5,600 crore from the current amount of approx. Rs 2,500 crore by 2015 as per an analysis of the trade in counterfeit luxury goods by the apex industry body, The Associated Chambers of Commerce and Industry of India (ASSOCHAM).

Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer

24th Thursday, 2013  |   Inflammation  |  no comments

Haabeth OAW, et al. Nature Communications Vol.2, No.240, 2011 doi:10.1038/ncomms1239

The immune system can both promote and suppress cancer. Chronic inflammation and proinflammatory cytokines such as interleukin (IL)-1 and IL-6 are considered to be tumour promoting. In contrast, the exact nature of protective antitumour immunity remains obscure. Here, we quantify locally secreted cytokines during primary immune responses against myeloma and B-cell lymphoma in mice. Strikingly, successful cancer immunosurveillance mediated by tumour-specific CD4+ T cells is consistently associated with elevated local levels of both proinflammatory (IL-1α, IL-1β and IL-6) and T helper 1 (Th1)-associated cytokines (interferon-γ (IFN-γ), IL-2 and IL-12). Cancer eradication is achieved by a collaboration between tumour-specific Th1 cells and tumour-infiltrating, antigen-presenting macrophages. Th1 cells induce secretion of IL-1β and IL-6 by macrophages. Th1-derived IFN-γ is shown to render macrophages directly cytotoxic to cancer cells, and to induce macrophages to secrete the angiostatic chemokines CXCL9/MIG and CXCL10/IP-10. Thus, inflammation, when driven by tumour-specific Th1 cells, may prevent rather than promote cancer.

They were crazy looking things,” Hyde said

23rd Wednesday, 2013  |   Uncategorized  |  no comments

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Sal DiNora, James Kain, Bill Ammatuna, Tony Modica, Joe

21st Monday, 2013  |   Uncategorized  |  no comments

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And of course, we serve Thailand, Singapore, and Australia

20th Sunday, 2013  |   Uncategorized  |  no comments

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