Acidity Generated by the Tumor Microenvironment Drives Local Invasion

Source: Estrella V, Chen T, Lloyd M, et al. Cancer Res March 1, 2013 73; 1524. doi: 10.1158/0008-5472.CAN-12-2796 The propensity of cancers to invade adjacent normal tissues contributes significantly to local tumor growth and formation of metastases, which are largely responsible for tumor-associated morbidity and mortality (1). The mechanisms by which tumor cells invade are […]

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