Clinical significance of macrophage heterogeneity in human malignant tumors with articles on down-regulating VEGF
It has long been known that many leukocytes including macrophages are present in tumor tissues and that these cells, together with fibroblasts and vascular endothelial cells, form the tumor microenvironment.[1-4] Previously, activated macrophages were believed to exhibit antitumor activity by directly attacking tumor cells in the tumor microenvironment.[5] However, many recent studies have indicated the […]
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