Increasing Obesity: Increasing Cancer
The estimated number of cancer cases linked to excess body fat is now at over 103,000 per year. With a new report showing that the rates of obesity continue to rise, Americans will likely experience a corresponding increase in the national cancer rate in the years ahead, say AICR experts.
read moreMore on Inflammation and Breast Cancer
The expression of transcripts of cytokines of the interleukin-6 (IL-6) family has been examined in human breast tumours, breast cancer cell lines, and adipose stromal cells, by means of reverse transcription polymerase chain reaction amplification.
read moreIn vivo Dynamics and Distinct Functions of Hypoxia in Primary Tumour Growth and Organotropic Metastasis of Breast Cancer
In vivo Dynamics and Distinct Functions of Hypoxia in Primary Tumour Growth and Organotropic Metastasis of Breast Cancer Tumour hypoxia is known to activate angiogenesis, anaerobic glycolysis, invasion, and metastasis.
read moreRisk Factors for Breast Cancer Recurrence and Systemic Disease; Locoregional tumour recurrence following breast-conserving surgery and radiotherapy raised risk for distant metastases.
Local and regional breast cancer recurrences are thought to be harbingers of distant disease. To study this potential association further, investigators analysed data from 2784 women (median age, 53) with early-stage breast cancer who underwent quadrantectomy and whole-breast radiation therapy at the European Institute of Oncology. Investigators sought to identify factors that predisposed patients to [...]
read moreCytokines and STATs in Cancer
Cytokines are known to have both stimulatory and inhibitory effects on breast cancer growth depending on their relative concentrations and the presence of other modulating factors in the tumour microenvironment. Certain cytokines appear to prevent an effective immune response being mounted, permitting cancer growth, whereas others promote the immune system’s anti-tumour capability.
read moreA simple blood test that will help your breast cancer patients understand their risk of re-occurrence and metastases.
A simple blood test that will help your breast cancer patients understand their risk of re-occurrence and metastases. Take a look at these references Elevated SAA and CRP were associated with reduced overall survival, regardless of adjustment for age, tumour stage, race, and body mass index (SAA p trend < .0001; CRP p trend = [...]
read moreCancer, Diet and Exercise
Diet is thought to be one of the most important contributing factors to cancer risk. The contribution of diet to cancer is linked to genetic factors but little has been shown as to cancer survival and diet (Bingham & Riboli 2004). One of the first thing patients ask about in a consultation after a diagnosis [...]
read moreSunscreen? I don't Think So Because Melanoma is Associated with Vitamin D Deficiency
Sunscreen? I don’t Think So Because Melanoma is Associated with Vitamin D Deficiency The form of vitamin D that acts most potently on the vitamin D receptor (VDR) in fighting cancer is 1,25-dihydroxyvitamin D (calcitriol). Calcitriol is a hormone that regulates calcium metabolism, and calcitriol levels are tightly regulated in the serum. The inverse association [...]
read moreDo inflammatory cytokines predict cancer?
Do inflammatory cytokines predict cancer? There are mixed reports on this and particularly on IL-6 levels but if we look at obesity and elevated IL-6, C-Reactive Protein and Serum Amyloid -A, I think we can find a positive prognosticator, despite the one report to the opposite. Serum interleukin-6 levels in colorectal cancer patients–a summary of [...]
read moreFour studies on vitamin use and cancer seem to reach different conclusions.
Four studies on vitamin use and cancer seem to reach different conclusions. Are vitamins a benefit or a danger? I guess like all of these studies it depends; depends on the type of vitamin, the form of the components ie methylate form or not, and the combinations of vitamins therein. I think it is wise [...]
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