Multivitamin use and breast cancer outcomes in women with early-stage breast cancer: the Life After Cancer Epidemiology study.
Little is known about the relation of multivitamin use to breast cancer outcomes. 2,236 women diagnosed from 1997 to 2000 with early-stage breast cancer (Stage I ≥ 1 cm, II, or IIIA) were enrolled about 2 years post-diagnosis, primarily from the Kaiser Permanente Northern California Cancer Registry (83%). Multivitamin use pre-diagnosis and post-diagnosis was assessed [...]
read moreConsensus Builds on High-Dose Vitamin D for Breast Cancer Prevention–Despite IOM Report
By Janet Gulland. Holistic primary Care. Vol. 11, No. 4. Winter, 2010 The role of vitamin D in cancer care was the subject of considerable attention at the recent Society for Integrative Oncology 7th annual assembly. Researchers and clinicians gathered at the meeting seemed to be moving toward a consensus that high-dose vitamin D supplementation [...]
read moreBreast Cancer
Eun Myoung Shin and Alan Prem Kumar. Innovation Journal 2012 Breast cancer is a cancer that starts in the tissue of the breast. There are two main types of breast cancer based on which part of breast tissue becomes cancerous (Figure 1). Ductal carcinoma starts in the tubes that move milk from the breast to [...]
read moreProgesterone Leads To Inflammation, A Breast Cancer Risk Factor, Research Reveals
Scientists at Michigan State University have found exposure to the hormone progesterone activates genes that trigger inflammation in the mammary gland. This progesterone-induced inflammation may be a key factor in increasing the risk of breast cancer. Progesterone is a naturally occurring steroid hormone and promotes development of the normal mammary gland. Progesterone previously has been [...]
read moreAnti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells.
Olive oil intake has been shown to induce significant levels of apoptosis in various cancer cells. These anti-cancer properties are thought to be mediated by phenolic compounds present in olive. These beneficial health effects of olive have been attributed, at least in part, to the presence of oleuropein and hydroxytyrosol. In this study, oleuropein and [...]
read moreGermacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis.
Traditional medicinal herbs are an untapped source of potential pharmaceutical compounds. This study aims to determine whether the proliferation of breast cancer cell lines could be inhibited by germacrone, a natural product isolated from Rhizoma curcuma. Germacrone treatment significantly inhibited cell proliferation, increased lactate dehydrogenase (LDH) release, and induced mitochondrial membrane potential (ΔΨm) depolarization in [...]
read moreOverview of resistance to systemic therapy in patients with breast cancer.
Breast cancer treatment is dismal and this report from MD Anderson does not sugar coat the sad truth that chemo resistance is the NORM. But they fail to tell you that it is worse than that because the cancer stem cells are virtually made tougher by the chemo. So it is more than resistance, it [...]
read moreEffects of platycodin D in combination with different active ingredients of Chinese herbs on proliferation and invasion of 4T1 and MDA-MB-231 breast cancer cell lines
OBJECTIVE: To investigate the effects of platycodin D in combination with different active ingredients of Chinese herbs under different therapeutic principles on proliferation and invasion of 4T1 and MDA-MB-231 breast cancer cell lines. METHODS: The effective doses of platycodin D, Ophiopogon total saponins, curcumenol and osthole in inhibiting proliferation of breast cancer cell lines 4T1 [...]
read moreTocotrienols fight cancer by targeting multiple cell signaling pathways.
Tocotrienols fight cancer by targeting multiple cell signaling pathways. Abstract: Cancer cells are distinguished by several distinct characteristics, such as self-sufficiency in growth signal, resistance to growth inhibition, limitless replicative potential, evasion of apoptosis, sustained angiogenesis, and tissue invasion and metastasis. Tumor cells acquire these properties due to the dysregulation of multiple genes and associated [...]
read moreLymph Node Study Shakes Pillar of Breast Cancer Care
By DENISE GRADY New York Times. Published: February 8, 2011 The discovery turns standard medical practice on its head. Surgeons have been removing lymph nodes from under the arms of breast cancer patients for 100 years, believing it would prolong women’s lives by keeping the cancer from spreading or coming back. Now, researchers report that [...]
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